• Report: Chinese Scientists Find "Killer Coronavirus Probably Originated From A Laboratory In Wuhan" (UNC Researchers Possibly Involved)

    February 16, 2020
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    Report: Chinese Scientist Finds "Killer Coronavirus Probably Originated From A Laboratory In Wuhan"
    Coronavirus replication
    Image by Crenim

    WARNING: You won't find this information in the legacy media

    A report from scientists in China is now projecting the novel coronavirus raging across the Middle Kingdom originated in the high-security bioweapons lab in Wuhan, where the outbreak began.

    The report describes how scientists in China herself have proposed the theory that the virus was released from the facility in question.

    An excerpt reads, The 2019-nCoV has caused an epidemic of 28,060 laboratory-confirmed infections in human including 564 deaths in China by February 6, 2020. Two descriptions of the virus published on Nature this week indicated that the genome sequences from patients were almost identical to the Bat CoV ZC45 coronavirus. It was critical to study where the pathogen came from and how it passed onto human. An article published on The Lancet reported that 27 of 41 infected patients were found to have contact with the Huanan Seafood Market in Wuhan. We noted two laboratories conducting research on bat coronavirus in Wuhan, one of which was only 280 meters from the seafood market. We briefly examined the histories of the laboratories and proposed that the coronavirus probably originated from a laboratory. Our proposal provided an alternative origin of the coronavirus in addition to natural recombination and intermediate host.

    “In summary, somebody was entangled with the evolution of 2019-nCoV coronavirus. In addition to origins of natural recombination and intermediate host, the killer coronavirus probably originated from a laboratory in Wuhan...”

    The entire report is printed at the end of this article, (hat tip to Zero Hedge).

    In other words, it didn't come from bats; it came from humans.

    Analysis from Harvard to the Big House outlines how highly-trained researchers from University of North Carolina traveled to China to work on the virus at the facility in question.

    And so a scientist who’s been prolifically involved with studying the molecular interaction of coronaviruses and humanity, spending decades and millions of dollars, and having even helped build a hyper-virulent coronavirus from scratch at UNC – just so happens to be working at the only BSL-4 virology lab in China that also just so happens to be at the epicenter of an outbreak involved a coronavirus that’s escaping zoological classification and whose novel spike-protein region shares more in common with a commercial genetic vector than any of its wild relatives, and has other unnatural characteristics that will be discussed below...

    And in a predictable turn, both researchers have since deleted their profiles off of the ResearchGate site completely. Additionally, the trend in reporting from the Chinese government diverged sharply on February 11th, when the paper initially was uploaded onto the site – making it appear as there’s internal infighting within the Party about what their official story will be...

    Simply and horribly, this is likely to become another Chernobyl or Fukushima – a catastrophic illustration of mankind’s hubris and intransigence clashing with Nature, as fate again reaps a once unimaginably tragic toll...

    In an interesting turn, the analysis relates to CD Media's reporting yesterday that the strain of virus was developed as a bioweapon to be deadly to only certain types of humans, possibly as a 'Red Team' threat for Chinese bioweapon researchers to learn to defend against.

    – Early research found that 2019-nCoV targets the ACE2 receptor, which is found in East Asians at roughly five-times the rate of other global populations, indicating that the Wuhan Strain 2019-nCoV was likely developed as part of a gain-of-function defensive project possibly linked to immunotherapy or vaccinations – never meant to leave the lab, but meant to serve as a Red Team to fight back against, not as an offensive weapon since the virus is likely wired to be much more virulent among Asian populations.

    The conclusion of the analysis...

    Chinese scientists failed to follow correct sanitation protocols possibly while in a rush during their boisterous holiday season, something that had been anticipated since the opening of the BSL-4 lab and has happened at least four times previously, and accidentally released this bio-engineered Wuhan Strain – likely created by scientists researching immunotherapy regimes against bat coronaviruses, who’ve already demonstrated the ability to perform every step necessary to bio-engineer the Wuhan Strain 2019-nCov – into their population, and now the world. As would be expected, this virus appears to have been bio-engineered at the spike-protein genes which was already done at UNC to make an extraordinarily virulent coronavirus. Chinese efforts to stop the full story about what’s going on are because they want the scales to be even since they’re now facing a severe pandemic and depopulation event. No facts point against this conclusion.

    The original Chinese report is below...

    ------------------------------------------------------------------------------

    The possible origins of 2019-nCoV coronavirus

    Botao Xiao1,2* and Lei Xiao3

    1 Joint International Research Laboratory of Synthetic Biology and Medicine, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China

    2 School of Physics, Huazhong University of Science and Technology, Wuhan 430074, China

    3 Tian You Hospital, Wuhan University of Science and Technology, Wuhan 430064, China

    Corresponding author: [email protected]

    Tel / Fax: 86-20-3938-0631

    The 2019-nCoV coronavirus has caused an epidemic of 28,060 laboratory-confirmed infections in human including 564 deaths in China by February 6, 2020. Two descriptions of the virus published on Nature this week indicated that the genome sequences from patients were 96% or 89% identical to the Bat CoV ZC45 coronavirus originally found in Rhinolophus affinis 1,2. It was critical to study where the pathogen came from and how it passed onto human.

    An article published on The Lancet reported that 41 people in Wuhan were found to have the acute respiratory syndrome and 27 of them had contact with Huanan Seafood Market 3. The 2019-nCoV was found in 33 out of 585 samples collected in the market after the outbreak. The market was suspected to be the origin of the epidemic, and was shut down according to the rule of quarantine the source during an epidemic.

    The bats carrying CoV ZC45 were originally found in Yunnan or Zhejiang province, both of which were more than 900 kilometers away from the seafood market. Bats were normally found to live in caves and trees. But the seafood market is in a densely-populated district of Wuhan, a metropolitan of ~15 million people. The probability was very low for the bats to fly to the marketAccording to municipal reports and the testimonies of 31 residents and 28 visitors, the bat was never a food source in the city, and no bat was traded in the market. There was possible natural recombination or intermediate host of the coronavirus, yet little proof has been reported.

    Was there any other possible pathway? We screened the area around the seafood market and identified two laboratories conducting research on bat coronavirus. Within ~280 meters from the market, there was the Wuhan Center for Disease Control & Prevention (WHCDC) (Figure 1, from Baidu and Google maps).

    WHCDC hosted animals in laboratories for research purpose, one of which was specialized in pathogens collection and identification 4- 6. In one of their studies, 155 bats including Rhinolophus affinis were captured in Hubei province, and other 450 bats were captured in Zhejiang province 4. The expert in collection was noted in the Author Contributions (JHT). Moreover, he was broadcasted for collecting viruses on nation-wide newspapers and websites in 2017 and 2019 7,8. He described that he was once attacked by bats and the blood of a bat shot on his skin. He knew the extreme danger of the infection so he quarantined himself for 14 days 7. In another accident, he quarantined himself again because bats peed on him. He was once thrilled for capturing a bat carrying a live tick8.

    Surgery was performed on the caged animals and the tissue samples were collected for DNA and RNA extraction and sequencing 4, 5. The tissue samples and contaminated trashes were source of pathogens. They were only ~280 meters from the seafood marketThe WHCDC was also adjacent to the Union Hospital (Figure 1, bottom) where the first group of doctors were infected during this epidemic. It is plausible that the virus leaked around and some of them contaminated the initial patients in this epidemic, though solid proofs are needed in future study.

    The second laboratory was ~12 kilometers from the seafood market and belonged to Wuhan Institute of Virology, Chinese Academy of Sciences 1, 9, 10This laboratory reported that the Chinese horseshoe bats were natural reservoirs for the severe acute respiratory syndrome coronavirus (SARS-CoV) which caused the 2002-3 pandemic 9The principle investigator participated in a project which generated a chimeric virus using the SARS-CoV reverse genetics system, and reported the potential for human emergence 10A direct speculation was that SARS-CoV or its derivative might leak from the laboratory.

    In summary, somebody was entangled with the evolution of 2019-nCoV coronavirus. In addition to origins of natural recombination and intermediate host, the killer coronavirus probably originated from a laboratory in Wuhan. Safety level may need to be reinforced in high risk biohazardous laboratories. Regulations may be taken to relocate these laboratories far away from city center and other densely populated places.

    Acknowledgements

    This work is supported by the National Natural Science Foundation of China (11772133, 11372116).

    Declaration of interests

    All authors declare no competing interests.

    References

    1. Zhou P, Yang X-L, Wang X-G, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020. https://doi.org/10.1038/s41586-020-2012-7.
    2. Wu F, Zhao S, Yu B, et al. A new coronavirus associated with human respiratory disease in China. Nature 2020. https://doi.org/10.1038/s41586-020-2008-3.
    3. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet 2019. https://doi.org/10.1016/S0140- 6736(20)30183-5.
    4. Guo WP, Lin XD, Wang W, et al. Phylogeny and origins of hantaviruses harbored by bats, insectivores, and rodents. PLoS pathogens 2013; 9(2): e1003159.
    5. Lu M, Tian JH, Yu B, Guo WP, Holmes EC, Zhang YZ. Extensive diversity of rickettsiales bacteria in ticks from Wuhan, China. Ticks and tick-borne diseases 2017; 8(4): 574-80.
    6. Shi M, Lin XD, Chen X, et al. The evolutionary history of vertebrate RNA viruses. Nature 2018; 556(7700): 197-202.
    7. Tao P. Expert in Wuhan collected ten thousands animals: capture bats in mountain at night. Changjiang Times 2017.
    8. Li QX, Zhanyao. Playing with elephant dung, fishing for sea bottom mud: the work that will change China's future. thepaper 2019.
    9. Ge XY, Li JL, Yang XL, et al. Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor. Nature 2013; 503(7477): 535-8.
    10. Menachery VD, Yount BL, Jr., Debbink K, et al. A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nature medicine 2015; 21(12): 1508-13.

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    James Carpenter Carpenter

    "Made in China"
    Coming to a WalMart near you soon (and just about everywhere else).

    Hohot

    2 Chinese researchers (as part of a team) at UNC Chapel Hill published a paper in 2015 where they altered a receptor on a Coronavirus found in horseshoe bats. This Chimeric virus grew in animals and test tubes so it was able to “jump” species. They claimed it was to proactively protect against a possible super virus by getting a vaccine. All attempts to do a vaccine failed. Their actions were criticized by others as irresponsible. They now work in Wuhan lab.

    SCIENCE magazine reports controversy:
    "The results demonstrate the ability of the SHC014 surface protein to bind and infect human cells, validating concerns that this virus—or other coronaviruses found in bat species—may be capable of making the leap to people without first evolving in an intermediate host, Nature reported. They also reignite a debate about whether that information justifies the risk of such work, known as gain-of-function research. “If the [new] virus escaped, nobody could predict the trajectory,” Simon Wain-Hobson, a virologist at the Pasteur Institute in Paris, told Nature.

    In October 2013, the US government put a stop to all federal funding for gain-of-function studies, with particular concern rising about influenza, SARS, and Middle East respiratory syndrome (MERS). “NIH [National Institutes of Health] has funded such studies because they help define the fundamental nature of human-pathogen interactions, enable the assessment of the pandemic potential of emerging infectious agents, and inform public health and preparedness efforts,” NIH Director Francis Collins said in a statement at the time. “These studies, however, also entail biosafety and biosecurity risks, which need to be understood better.”

    Baric’s study on the SHC014-chimeric coronavirus began before the moratorium was announced, and the NIH allowed it to proceed during a review process, which eventually led to the conclusion that the work did not fall under the new restrictions, Baric told Nature. But some researchers, like Wain-Hobson, disagree with that decision.
    The debate comes down to how informative the results are. “The only impact of this work is the creation, in a lab, of a new, non-natural risk,” Richard Ebright, a molecular biologist and biodefence expert at Rutgers University, told Nature. https://www.the-scientist.com/news-opinion/lab-made-coronavirus-triggers-debate-34502

    Original paper. https://www.the-scientist.com/news-opinion/lab-made-coronavirus-triggers-debate-34502

    Michaenc58

    From the targeting ACE2 reference:
    "... this new virus showed that its S protein only binds weakly to the ACE2 receptor on human cells whereas the human SARS coronavirus exhibits strongly affinity to the ACE receptor."

    I suspect it is a man-made virus, but the reference suggests this virus is much less specific to Asians than SARS was, so argues against your article's thesis, no?.

    D3F1ANT

    I'm way behind the curve...I thought we were taking the fact that the Chinese are behind the Coronavirus as a given!

    A A Ron

    Maybe this was not an accidental release, but a test run. Let's get something relatively 'weak' out there and see how it prorogates, so if there is a major issue, it is relatively easy to clean up, and once we figure out how it works and spreads, we will fine tune the 'American' version of it that goes after Mr. Round eye and see how eager they are to make a trade deal then?

    trackback

    […] “– Early research found that 2019-nCoV targets the ACE2 receptor, which is found in East Asians at roughly five-times the rate of other global populations, indicating that the Wuhan Strain 2019-nCoV was likely developed as part of a gain-of-function defensive project possibly linked to immunotherapy or vaccinations – never meant to leave the lab, but meant to serve as a Red Team to fight back against, not as an offensive weapon since the virus is likely wired to be much more virulent among Asian populations. […]

    […] Report: Chinese Scientists Find “Killer Coronavirus Probably Originated From A Laboratory In Wuhan… […]

    […] Report: Chinese Scientists Find “Killer Coronavirus Probably Originated From A Laboratory In Wuhan… […]

    Robert

    The Chinese paid a North Carolina University for a scientist to do work there and was involved in the virus itself he also works at the bio lab in Hunan where they make bio weapons and now the virus has somehow escaped through some means. Seem maybe the Chinese stole the virus and took it back to china. These are the rumors I'm hearing.

    anonymous

    Article from 2015

    https://www.the-scientist.com/news-opinion/lab-made-coronavirus-triggers-debate-34502?archived_content=9BmGYHLCH6vLGNdd9YzYFAqV8S3Xw3L5

    Lab-Made Coronavirus Triggers Debate
    The creation of a chimeric SARS-like virus has scientists discussing the risks of gain-of-function research.
    Jef Akst
    Nov 16, 2015
    34.5K

    MERS coronavirus
    FLICKR, NIAID
    Ralph Baric, an infectious-disease researcher at the University of North Carolina at Chapel Hill, last week (November 9) published a study on his team’s efforts to engineer a virus with the surface protein of the SHC014 coronavirus, found in horseshoe bats in China, and the backbone of one that causes human-like severe acute respiratory syndrome (SARS) in mice. The hybrid virus could infect human airway cells and caused disease in mice, according to the team’s results, which were published in Nature Medicine. (cont'd at link)

    […] that it came from the govt labs. And it’s not just twitter now, it’s being printed more and more and more (and more—I won’t link to the Wapo article since they have a paywall that I can’t […]

    […] CDMedia has reported extensively on the origins of the virus, but what was done to divide the country along party lines? Beyond the hydroxychloroquine battle. Beyond bad modeling that called for millions of deaths. […]

    […] CDMedia has reported extensively on the origins of the virus, but what was done to divide the country along party lines? Beyond the hydroxychloroquine battle. Beyond bad modeling that called for millions of deaths. […]

    waterfallmagazine.com

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